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1

Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial

Robert, Caroline, Ribas, Antoni, Wolchok, Jedd D, Hodi, F Stephen, Hamid, Omid, Kefford, Richard, Weber, Jeffrey S, Joshua, Anthony M, Hwu, Wen-Jen, Gangadhar, Tara C, Patnaik, Amita, Dronca, Roxana,

Journal:

Year:

2014

Language:

english

File:

PDF, 364 KB

english, 2014

2

Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial

Eggermont, Alexander M M, Chiarion-Sileni, Vanna, Grob, Jean-Jacques, Dummer, Reinhard, Wolchok, Jedd D, Schmidt, Henrik, Hamid, Omid, Robert, Caroline, Ascierto, Paolo A, Richards, Jon M, Lebbé, Céle

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

3

Cancer immunotherapy using checkpoint blockade

Ribas, Antoni, Wolchok, Jedd D.

Journal:

Year:

2018

Language:

english

File:

PDF, 668 KB

english, 2018

4

Putting the Immunologic Brakes on Cancer

Journal:

Year:

2018

Language:

english

File:

PDF, 490 KB

english, 2018

5

Anti–CTLA-4 Antibody Therapy: Immune Monitoring During Clinical Development of a Novel Immunotherapy

Margaret K. Callahan, Jedd D. Wolchok, James P. Allison

Journal:

Seminars in Oncology

Year:

2010

Language:

english

File:

PDF, 693 KB

english, 2010

6

The role of lipopolysaccharide in T-cell responses following DNA vaccination

William G. Hawkins, Jiri Trcka, Neil Segal, Nathalie E. Blachere, Jason S. Gold, Yoichi Moroi, Wilbur B. Bowne, Jonathan J. Lewis, Jedd D. Wolchok, Alan N. Houghton

Journal:

Year:

2003

Language:

english

File:

PDF, 113 KB

english, 2003

7

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

Hamid, Omid, Robert, Caroline, Daud, Adil, Hodi, F. Stephen, Hwu, Wen-Jen, Kefford, Richard, Wolchok, Jedd D., Hersey, Peter, Joseph, Richard W., Weber, Jeffrey S., Dronca, Roxana, Gangadhar, Tara C.,

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 701 KB

english, 2013

8

Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma

Wolchok, Jedd D., Hodi, F. Stephen, Weber, Jeffrey S., Allison, James P., Urba, Walter J., Robert, Caroline, O'Day, Steven J., Hoos, Axel, Humphrey, Rachel, Berman, David M., Lonberg, Nils, Korman, Al

Journal:

Annals of the New York Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 733 KB

english, 2013

9

Nivolumab plus Ipilimumab in Advanced Melanoma

Wolchok, Jedd D., Kluger, Harriet, Callahan, Margaret K., Postow, Michael A., Rizvi, Naiyer A., Lesokhin, Alexander M., Segal, Neil H., Ariyan, Charlotte E., Gordon, Ruth-Ann, Reed, Kathleen, Burke, M

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 646 KB

english, 2013

10

PD-1 Blockers

Wolchok, Jedd D.

Journal:

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

11

Targeting cytotoxic T-lymphocyte antigen 4 in immunotherapies for melanoma and other cancers

Page, David B, Yuan, Jianda, Wolchok, Jedd D

Journal:

Year:

2010

Language:

english

File:

PDF, 2.73 MB

english, 2010

12

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

Khalil, Danny N., Smith, Eric L., Brentjens, Renier J., Wolchok, Jedd D.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2016

Language:

english

File:

PDF, 646 KB

english, 2016

13

Patient-Physician Communication in the 21st Century

Friedman, Claire F., Wolchok, Jedd D.

Journal:

Trends in Immunology

Year:

2016

Language:

english

File:

PDF, 346 KB

english, 2016

14

Potentiation of immunomodulatory antibody therapy with oncolytic viruses for treatment of cancer

Zamarin, Dmitriy, Wolchok, Jedd D

Journal:

Molecular Therapy — Oncolytics

Year:

2014

Language:

english

File:

PDF, 2.11 MB

english, 2014

15

Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications

Shia, Jinru, Schultz, Nikolaus, Kuk, Deborah, Vakiani, Efsevia, Middha, Sumit, Segal, Neil H, Hechtman, Jaclyn F, Berger, Michael F, Stadler, Zsofia K, Weiser, Martin R, Wolchok, Jedd D, Boland, C Ric

Journal:

Modern Pathology

Year:

2017

Language:

english

File:

PDF, 2.88 MB

english, 2017

16

Cancer immunotherapy — immune checkpoint blockade and associated endocrinopathies

Byun, David J., Wolchok, Jedd D., Rosenberg, Lynne M., Girotra, Monica

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2017

Language:

english

File:

PDF, 672 KB

english, 2017

17

Curbing Tregs’ (Lack of) Enthusiasm

Merghoub, Taha, Wolchok, Jedd D.

Journal:

Year:

2017

Language:

english

File:

PDF, 228 KB

english, 2017

18

Introduction by the Guest Editors

Wolchok, Jedd D., Callahan, Margaret K.

Journal:

The Cancer Journal

Year:

2018

Language:

english

File:

PDF, 48 KB

english, 2018

19

Introducing a New Series: Immunotherapy Facts and Hopes

Melero, Ignacio, Sznol, Mario, Tessmer, Marlowe S., Whiteside, Theresa L., Wolchok, Jedd D.

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 163 KB

english, 2018

20

Efficacy and Safety Outcomes in Patients With Advanced Melanoma Who Discontinued Treatment With Nivolumab and Ipilimumab Because of Adverse Events: A Pooled Analysis of Randomized Phase II and III Trials

Schadendorf, Dirk, Wolchok, Jedd D., Hodi, F. Stephen, Chiarion-Sileni, Vanna, Gonzalez, Rene, Rutkowski, Piotr, Grob, Jean-Jacques, Cowey, C. Lance, Lao, Christopher D., Chesney, Jason, Robert, Carol

Journal:

Journal of Clinical Oncology

Year:

2017

File:

PDF, 1005 KB

2017

21

Adjuvant ipilimumab versus placebo after complete resection of stage III melanoma: long-term follow-up results of the European Organisation for Research and Treatment of Cancer 18071 double-blind phase 3 randomised trial

Eggermont, Alexander M.M., Chiarion-Sileni, Vanna, Grob, Jean-Jacques, Dummer, Reinhard, Wolchok, Jedd D., Schmidt, Henrik, Hamid, Omid, Robert, Caroline, Ascierto, Paolo Antonio, Richards, Jon M., Le

Journal:

European Journal of Cancer

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

22

Temozolomide plus thalidomide in patients with brain metastases from melanoma : A Phase II study

Wen-Jen Hwu, Eric Lis, Jennifer H. Menell, Katherine S. Panageas, Lynne A. Lamb, Janene Merrell, Linda J. Williams, Susan E. Krown, Paul B. Chapman, Philip O. Livingston, Jedd D. Wolchok, Alan N. Houg

Journal:

Year:

2005

Language:

english

File:

PDF, 98 KB

english, 2005

23

Phase II study of temozolomide plus pegylated interferon-α-2b for metastatic melanoma

Wen-Jen Hwu, Katherine S. Panageas, Jennifer H. Menell, Lynne A. Lamb, Suzan Aird, Susan E. Krown, Linda J. Williams, Paul B. Chapman, Philip O. Livingston, Jedd D. Wolchok, Alan N. Houghton

Journal:

Year:

2006

Language:

english

File:

PDF, 100 KB

english, 2006

24

Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting : Lymphocyte count after 2 doses correlates with survival

Geoffrey Y. Ku, Jianda Yuan, David B. Page, Sebastian E. A. Schroeder, Katherine S. Panageas, Richard D. Carvajal, Paul B. Chapman, Gary K. Schwartz, James P. Allison, Jedd D. Wolchok

Journal:

Year:

2010

Language:

english

File:

PDF, 296 KB

english, 2010

25

Induction of autoantibodies to syngeneic prostate-specific membrane antigen by xenogeneic vaccination

Polly D. Gregor, Jedd D. Wolchok, Vandana Turaga, Jean-Baptiste Latouche, Michel Sadelain, Dean Bacich, Warren D.W. Heston, Alan N. Houghton, Howard I. Scher

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

26

Multiple pathways to tumor immunity and concomitant autoimmunity

Mary Jo Turk, Jedd D. Wolchok, José A. Guevara-Patino, Stacie M. Goldberg, Alan N. Houghton

Journal:

Immunological Reviews

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

27

WT1 peptide vaccinations induce CD4 and CD8 T cell immune responses in patients with mesothelioma and non-small cell lung cancer

Lee M. Krug, Tao Dao, Andrew B. Brown, Peter Maslak, William Travis, Sara Bekele, Tatyana Korontsvit, Victoria Zakhaleva, Jedd Wolchok, Jianda Yuan, Hao Li, Leslie Tyson, David A. Scheinberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

28

Dual Mode Reflectance and Fluorescence Confocal Laser Scanning Microscopy for In Vivo Imaging Melanoma Progression in Murine Skin

Li, Yanyun, Gonzalez, Salvador, Terwey, Theis H, Wolchok, Jedd, Li, Yongbiao, Aranda, Iana, Toledo-Crow, Ricardo, Halpern, Allan C

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 3.87 MB

english, 2005

29

Diffuse melanosis after chemotherapy-induced tumor lysis syndrome in a patient with metastatic melanoma

Klaus J. Busam, Jedd Wolchok, Achim A. Jungbluth, Paul Chapman

Journal:

Journal of Cutaneous Pathology

Year:

2004

Language:

english

File:

PDF, 2.32 MB

english, 2004

30

Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

Sharma, Padmanee, Wagner, Klaus, Wolchok, Jedd D., Allison, James P.

Journal:

Nature Reviews Cancer

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

31

Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity

Ramirez-Montagut, Teresa, Turk, Mary Jo, Wolchok, Jedd D, Guevara-Patino, José A, Houghton, Alan N

Journal:

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

32

CD4 Help and Tumor Immunity: Beyond the Activation of Cytotoxic T Lymphocytes

Miguel-Angel Perales, Jedd D. Wolchok

Journal:

Annals of Surgical Oncology

Year:

2004

Language:

english

File:

PDF, 30 KB

english, 2004

33

Stage-IV Melanoma and Pulmonary Metastases: Factors Predictive of Survival

Heather B. Neuman, Ami Patel, Christine Hanlon, Jedd D. Wolchok, Alan N. Houghton, Daniel G. Coit

Journal:

Annals of Surgical Oncology

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

34

Antibody therapy of cancer

Scott, Andrew M., Wolchok, Jedd D., Old, Lloyd J.

Journal:

Nature Reviews Cancer

Year:

2012

Language:

english

File:

PDF, 826 KB

english, 2012

35

Strategies to overcome immune ignorance and tolerance

Miguel-Angel Perales, Nathalie E. Blachere, Manuel E. Engelhorn, Cristina R. Ferrone, Jason S. Gold, Polly D. Gregor, Gabriele Noffz, Jedd D. Wolchok, Alan N. Houghton

Journal:

Seminars in Cancer Biology

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

36

The role of the immune system in early epithelial carcinogenesis: B-ware the double-edged sword

Alan N. Houghton, Hiroshi Uchi, Jedd D. Wolchok

Journal:

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005

37

DNA vaccines: an active immunization strategy for prostate cancer

Jedd D Wolchok, Polly D Gregor, Luke T Nordquist, Susan F Slovin, Howard I Scher

Journal:

Seminars in Oncology

Year:

2003

Language:

english

File:

PDF, 128 KB

english, 2003

38

Completely Regressed Cutaneous Melanocytic Lesion: Was It Benign or Was It Malignant?

Adam C. Berger, Edward F. McClay, Mary Toporcer, Jedd D. Wolchok, Gloria J. Morris

Journal:

Seminars in Oncology

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

39

Alan Houghton

Jedd Wolchok, Paul Chapman

Journal:

Pigment Cell & Melanoma Research

Year:

2012

Language:

english

File:

PDF, 62 KB

english, 2012

40

Surgical management of melanoma of the gallbladder: a report of 13 cases and review of the literature

Steven C. Katz, Wilbur B. Bowne, Jedd D. Wolchok, Klaus J. Busam, David P. Jaques, Daniel G. Coit

Journal:

The American Journal of Surgery

Year:

2007

Language:

english

File:

PDF, 108 KB

english, 2007

41

Modulation of GITR for cancer immunotherapy

David A Schaer, Judith T Murphy, Jedd D Wolchok

Journal:

Current Opinion in Immunology

Year:

2012

Language:

english

File:

PDF, 819 KB

english, 2012

42

CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems

Polly D. Gregor, Jedd D. Wolchok, Cristina R. Ferrone, Heidi Buchinshky, Jose A. Guevara-Patiño, Miguel-Angel Perales, Fariborz Mortazavi, Dean Bacich, Warren Heston, Jean-Baptiste Latouche, Michel Sa

Journal:

Year:

2004

Language:

english

File:

PDF, 213 KB

english, 2004

43

Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes

Colin S.B. Houghton, Manuel E. Engelhorn, Cailan Liu, Da Song, Polly Gregor, Phillip O. Livingston, Francesca Orlandi, Jedd D. Wolchok, James McCracken, Alan N. Houghton, José A. Guevara-Patiño

Journal:

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

44

Development of effective vaccines for old mice in a tumor model

David N. Posnett, Manuel E. Engelhorn, Yun Lin, Taha Merghoub, Fei Duan, Jedd D. Wolchok, Alan N. Houghton

Journal:

Year:

2009

Language:

english

File:

PDF, 890 KB

english, 2009

45

Combination of epitope-optimized DNA vaccination and passive infusion of monoclonal antibody against HER2/neu leads to breast tumor regression in mice

Francesca Orlandi, José A. Guevara-Patiño, Taha Merghoub, Jedd D. Wolchok, Alan N. Houghton, Polly D. Gregor

Journal:

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

46

Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

Jedd D Wolchok, Bart Neyns, Gerald Linette, Sylvie Negrier, Jose Lutzky, Luc Thomas, William Waterfield, Dirk Schadendorf, Michael Smylie, Troy Guthrie Jr, Jean-Jacques Grob, Jason Chesney, Kevin Chin

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 246 KB

english, 2010

47

Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial

Kim Margolin, Marc S Ernstoff, Omid Hamid, Donald Lawrence, David McDermott, Igor Puzanov, Jedd D Wolchok, Joseph I Clark, Mario Sznol, Theodore F Logan, Jon Richards, Tracy Michener, Agnes Balogh, Ke

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 129 KB

english, 2012

48

Immunization with DNA coding for gp100 results in CD4+ T-cell independent antitumor immunity

William G. Hawkins, Jason S. Gold, Ruben Dyall, Jedd D. Wolchok, Axel Hoos, Wilbur B. Bowne, Roopa Srinivasan, Alan N. Houghton, Jonathan J. Lewis

Journal:

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

49

Meeting Report: Fourth International Congress of the Society for Melanoma Research

David E. Fisher, Estela E. Medrano, Martin McMahon, Marisol S. Soengas, Lynn Schuchter, Jedd D. Wolchok, Glenn Merlino

Journal:

Pigment Cell & Melanoma Research

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

50

Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas

Piro Lito, Christine A. Pratilas, Eric W. Joseph, Madhavi Tadi, Ensar Halilovic, Matthew Zubrowski, Alan Huang, Wai Lin Wong, Margaret K. Callahan, Taha Merghoub, Jedd D. Wolchok, Elisa de Stanchina,

Journal:

Year:

2012

Language:

english

File:

PDF, 2.16 MB

english, 2012

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